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Image Search Results
Journal: The American journal of pathology
Article Title: Low-dose-rate, low-dose irradiation delays neurodegeneration in a model of retinitis pigmentosa.
doi: 10.1016/j.ajpath.2011.09.025
Figure Lengend Snippet: Figure 4. Prdx2 plays a major role in the neuroprotective effects induced by low-dose-rate, low-dose (LDR-LD) radiation. A: Time course of Prdx2 mRNA levels in LDR-LD–irradiated retinas (n 6). B: Western blot analysis of Prdx2 in LDR-LD–irradiated retinas (n 9). C–F: In situ hybridization study of Prdx2 in the retina. G–J: Immunohistochemistry of Prdx2 in the retina. K: Relative expression level of Prdx2 mRNA 26 hours after intravitreal siRNA injection. Radiation was administered at 24 hours after injection. NC, negative control injected; Rad, LDR-LD radiation (n 12). A normal C57BL/6 strain was used in experiments A to K. L: PRL thickness of an rd10 (P25) mouse retina. Intravitreal injection of siRNA at P18. LDR-LD radiation was performed 24 hours after the siRNA injection (P19) (n 12). Scale bars: 60 m (C–J). *P 0.05, **P 0.01 versus control. P values were from post hoc analysis.
Article Snippet: For the
Techniques: Irradiation, Western Blot, In Situ Hybridization, Immunohistochemistry, Expressing, Injection, Negative Control, Control